Bioavailability and Lag
[Generated automatically as a Tutorial summary]
Model Description
- Name:
biolag_abs_bio
- Title:
Bioavailability and Lag
- Author:
PoPy for PK/PD
- Abstract:
One compartment model absorption dosing with bioavailability and lag parameters.
- Keywords:
identifiability; bioavailability; lag
- Input Script:
- Diagram:
Comparison
True objective value
44.2050
Final fitted objective value
38.7412
Compare Main f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[KA] |
0.5 |
1 |
0.3 |
7.00e-01 |
233.33% |
f[CL] |
1 |
3.54 |
3 |
5.36e-01 |
17.87% |
f[V] |
15 |
14 |
20 |
6.04e+00 |
30.22% |
f[BIO] |
0.8 |
0.402 |
0.583 |
1.81e-01 |
30.98% |
f[LAG] |
1 |
9.2 |
0 |
9.20e+00 |
inf |
Compare Noise f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[ANOISE_STD] |
5 |
0.894 |
1 |
1.06e-01 |
10.65% |
Compare Variance f[X]
No Variance f[X] values to compare.
Outputs
Fitted f[X] values (after fitting)
f[KA] = 1.0000
f[CL] = 3.5361
f[V] = 13.9552
f[ANOISE_STD] = 0.8935
f[BIO] = 0.4024
f[LAG] = 9.2035
Generated data .csv file
- Synthetic Data:
Gen and Fit Summaries
Gen: Bioavailability and Lag (gen)
Fit: Bioavailability and Lag (fit)
Inputs
True f[X] values (for simulation)
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 0.5830
f[LAG] = 0.0000
Starting f[X] values (before fitting)
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.8000
f[LAG] = 1.0000